Electrical characteristics of frog atrial trabeculae in the double sucrose gap
نویسندگان
چکیده
منابع مشابه
Limitations of the double sucrose gap voltage clamp technique in tension-voltage determinations on frog atrial muscle.
The purpose of this study was to evaluate the limitations of the double sucrose gap voltage clamp technique in the determination of tension-voltage relationships for frog atrial muscle. Tension-voltage relationships were determined under two conditions. In one case we determined both the tension response and slow inward current associated with an apparent step depolarization (step-clamp) as a f...
متن کاملVoltage Clamp Analysis of Repetitive Firing in Frog Atrial Trabeculae
The membrane currents responsible for induced pace-maker activity in frog atrial muscle were investigated using a double sucrose gap technique. The trabecula was clamped to the potential from which pace-making started (35—40 mV positive to resting potential) and immediately after that a test pulse was applied and the membrane inward current was measured. When the duration of the conditioning pu...
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Voltage clamp experiments were performed to analyse the influence of the slow inward current (isi) on the repolarisation process in frog atrium. MnCl2 was used as isi blocker. The action potential was prolonged by depolarising pulses applied during the plateau. This was an expected result considering that, at positive potentials the time constant for isi inactivation increases. This effect was ...
متن کاملEffects of chloride replacement and chloride transport blockade on the tonic tension of frog atrial trabeculae.
The effects of a chloride-poor medium (methanesulfonate substituted) and a chloride transport inhibitor (SITS) on the outward delayed current and the tonic tension were studied on frog atrial trabeculae under voltage-clamp conditions. The outward delayed current decreased in low-chloride medium (10.5 mmol/l) or in the presence of SITS (2 mmol/l). The tonic tension increased in chloride-poor sol...
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چکیده یکی از مهمترین دغدغه های بزرگ جوامع بشری، از دیر باز تا کنون که ذهن پژوهشگران و متخصصان بهداشت روانی و اجتماعی و دولتها رابه خود مشغول داشته، مسأله ی بزهکاری می باشد. شناخت کامل پدیده ی بزهکاری و بزهکار، علل وعوامل سقوط یک انسان، چگونگی درمان وی و درنهایت پیشگیری ازبزهکاری ودریک کلام سالم سازی یک جامعه، رسالت عظیم، انسانی ومقدسی می باشد که با بررسی شخصیت مجرم یعنی[ انسانی که تحت شرای...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 1975
ISSN: 0006-3495
DOI: 10.1016/s0006-3495(75)85882-6